Biological Sciences

Biological Sciences

Biological Sciences Building

5007 Rockhill Road

http://sbc.umkc.edu/

Research facilities and laboratories

Equipment and Core Facilities

Microscope core facility on the ground floor in our building and overseen by the PI houses:

  1. Olympus Fluoview 300 confocal laser scanning microscope (CLSM) with DIC optics and four PMT detectors, three for epi-confocal imaging, and one for transmitted-light imaging. Argon 488 nm and He/Ne lasers are installed on the microscope.
  2. Nikon upright fluorescence microscope with a GRID confocal imaging device and Metamorph Image acquisition software for real time fluorescence imaging.
  3. Nikon inverted fluorescent DIC microscope with APO quality optics, four filter sets, and attached ColorView CCD camera with computer and Analysis software to analyze images.
  4. Olympus microscope with a range of objectives and filters attached to a CCD camera linked to a Silicon Graphics O2 loaded with Deltavision software for image acquisition and analysis (deconvolution).

Genomics core facility located on the second floor of the building overseen by a dedicated technician and directed by the PI includes:

(1) Allegra 25 centrifuge and two tetrad PCR machines for 96-well based applications

(3) Amersham Storm 860 Imaging System

(4) Amersham Typhoon 9400 phosphoimager with ImageQuant software

Protein core facility capable of mass spectrometry sample preparation and analysis is directed by Dr. Andrew Keightly and is located on the 4th floor of our building includes:

  1. Thermo Finnigan LTQ linear ion trap, equipped with Proxeon nanospray source
  2. Voyager DE Pro MALDI MS
  3. Eksigent binary nano-LC pump system (1D nanoLC)
  4. Eksigent quaternary nano-LC pump system (2D nanoLC)

X-ray crystallographic data are collected at beamlines 22ID and 22BM at the Advanced Photon Source of Argonne National Laboratory.  Access to these beamlines is guaranteed for 24 hours on each beamline (three times a year) through our membership to the Southeast Regional Collaborative Access Team (SER-CAT).